★★☆Single study — solid evidence, such as one good trial or a large observational dataset, but not replicated at the top tier.
A fruiting-body capsule cannot be carrying the erinacines
Mycelium grown in liquid culture made all four erinacines; six fruiting-body samples had none. They are the only lion's mane compounds measured entering a brain.
What the study found
Fruiting body carried none of the four erinacines measured
Mycelium grown in liquid culture made all four; six fruiting-body samples showed none. Erinacines are the only lion's mane compounds ever measured entering a brain and the ones used in the longest human trial, so a fruiting-body-only capsule cannot be delivering them.
The caveat · Test's detection limit not given
The mycelium here grew in stirred liquid, not on grain, so this settles which tissue makes erinacines and not how much of a grain-grown powder is mushroom. Only four erinacines were measured, and the assay's detection floor is not stated.