SubEx
Vitamin D3 (Cholecalciferol)·Support immunity·finding 16 of 20
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★☆☆Contested — the evidence disagrees with itself, or the finding carries a caution. A caution or conflict always shows one star, however strong the sources are.

Immune · decreases · contested

In one trial, new autoimmune disease fell by about a fifth

Over five years, 123 people on vitamin D3 developed a confirmed autoimmune condition against 155 on placebo. The p value lands exactly on 0.05.

What the study found

Five years of vitamin D3 cut new autoimmune disease by a fifth

In the same trial that found nothing for cancer, heart disease, fractures or depression, 123 people on vitamin D3 developed a confirmed autoimmune condition against 155 on placebo, a 22 percent reduction. It is the one clearly positive disease result that trial produced.

The caveat · Lands exactly on the chance line

The p value lands exactly on 0.05 and the interval nearly touches no effect, which makes this a fragile positive rather than a settled one. The count pools rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis together and tests none of them individually. Participants averaged 67 years old.

What we don't know

The p value lands exactly on 0.05 and the interval nearly touches no effect, which makes this a fragile positive rather than a settled one. The count pools rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis together and tests none of them individually. Participants averaged 67 years old.