SubEx
Vitamin D3 (Cholecalciferol)·Protect bones and joints·finding 20 of 20
★☆☆Contested — the evidence disagrees with itself, or the finding carries a caution. A caution or conflict always shows one star, however strong the sources are.

Other · contested

The same blood result is deficient or fine, depending who reads it

The Endocrine Society calls anything below 30 nanograms per millilitre deficient. The National Institutes of Health uses 20, and some bodies use 12.

What the study found

No two authorities agree where deficiency begins

The Endocrine Society calls anything below 30 nanograms per millilitre of 25-hydroxyvitamin D deficient. The National Institutes of Health uses 20, and some bodies use 12. The US Preventive Services Task Force says no single cut point defines it, because requirements differ between people.

The caveat · Set for populations, not one person

The 20 nanogram figure was set as a population planning number covering the needs of nearly everyone, not as a line for diagnosing one person, and the committee that set it has said so in print. The Institute of Medicine derived it from bone health alone, having found the evidence on cancer, heart disease, diabetes and infection too thin to set requirements on. Which number a person is measured against decides whether they are told they have a problem.

What we don't know

Where vitamin D deficiency begins is unsettled: expert lines sit at 30, 20 and 12 nanograms per millilitre. Evidence cannot choose between them, because no trial has tested whether measuring a level and acting on it does anyone good.