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★★★Well replicated — this finding’s sources average out to meta-analyses, systematic reviews or high-powered trials.
The review could reach no conclusion on D-chiro-inositol
Of 48 studies, 42 were of metformin and two of D-chiro-inositol. Neither of those reported live birth or gut side effects, the review's main outcomes.
What the study found
D-chiro-inositol got two of Cochrane's forty-eight studies
Metformin accounted for 42 of them. Neither D-chiro-inositol study reported live birth or gastrointestinal side effects, the review's two primary outcomes, so the reviewers stated they could draw no conclusion about it at all.
The caveat · Left out the form most people take
This is an absence of evidence, not evidence that D-chiro-inositol does nothing. Myo-inositol sat outside the review entirely, so nothing here describes the form most people actually take. The search closed in January 2017.