SubEx
Diphenhydramine·Sleep better·finding 20 of 26
★☆☆Contested — the evidence disagrees with itself, or the finding carries a caution. A caution or conflict always shows one star, however strong the sources are.

Physical & body · contested

Teen harms came far more often with suspected suicide than misuse

Across 47,644 ingestions by 13 to 19 year olds over fourteen years, seizures, comas and deaths were markedly more common in suspected suicide than in misuse.

What the study found

Serious teen harms came more often after suspected suicide than misuse

Across 47,644 diphenhydramine ingestions by 13 to 19 year olds over fourteen years, cardiac complications, seizures, comas and deaths were markedly more common in suspected suicide than in misuse or abuse. A 2020 US regulator's warning had targeted the misuse.

The caveat · Intent coded during a phone call

The authors do not say the misuse is harmless, only that the self-harm cases carried the worse outcomes. Intent is coded by whoever takes the phone call, and the line between misuse and a suicide attempt is drawn there. The warning itself would have lifted reporting.

What we don't know

The authors do not say the misuse is harmless, only that the self-harm cases carried the worse outcomes. Intent is coded by whoever takes the phone call, and the line between misuse and a suicide attempt is drawn there. The warning itself would have lifted reporting.