The big win over metformin comes with an interval from 2.31 to 93.58
In a network comparison of 22 trials, the myo-inositol and D-chiro-inositol blend beat metformin on menstrual frequency at odds of 14.70. The interval runs from 2.31 to 93.58.
What the study found
A fourteenfold edge over metformin, with an interval to match
In a network comparison of 22 trials, the myo-inositol plus D-chiro-inositol combination beat metformin on menstrual frequency at an odds ratio of 14.70. The interval runs from 2.31 to 93.58, a spread that signals sparse data rather than a large reliable effect.
The caveat · Indirect, never tested head to head
A network meta-analysis mostly compares treatments that were never tested against each other directly, so this is an indirect estimate. Twenty-two trials and 1079 women spread across four classes of treatment leaves each comparison thin. Nothing here goes beyond a surrogate: no pregnancy, no live birth.
What we don't know
A network meta-analysis mostly compares treatments that were never tested against each other directly, so this is an indirect estimate. Twenty-two trials and 1079 women spread across four classes of treatment leaves each comparison thin. Nothing here goes beyond a surrogate: no pregnancy, no live birth.