SubEx
Venlafaxine·Support mood·finding 08 of 12
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★☆☆Contested — the evidence disagrees with itself, or the finding carries a caution. A caution or conflict always shows one star, however strong the sources are.

Mood & wellbeing · not established · contested

Most who tapered with strips and replied years later were still off

Of 824 people using the strips, most after earlier failed attempts, 72% stopped; of 408 asked one to five years later, 66% were still off. Nobody tapered without strips for comparison.

What the study found

Two in three tapering-strip users were still off the drug years on

Tapering strips are rolls of daily pouches of slowly falling doses, made in the Netherlands. Of 824 users, most after earlier failures, 72% stopped over a median 56 days, venlafaxine users most often of the three drug groups. Of 408 surveyed one to five years on, 66% were still off.

The caveat · No comparison group without strips

Nobody tapered without the strips for comparison, so the figures describe the users, not the strips' effect. Response rates were 48% and 59%, and outcomes were self-reported, some recalled from up to five years earlier. The authors' institute received a grant from the pharmacy that makes the strips.

What we don't know

Nobody tapered without the strips for comparison, so the figures describe the users, not the strips' effect. Response rates were 48% and 59%, and outcomes were self-reported, some recalled from up to five years earlier. The authors' institute received a grant from the pharmacy that makes the strips.