SubEx
Soy Isoflavones·Balance hormones·finding 04 of 26
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★★★Well replicated — this finding’s sources average out to meta-analyses, systematic reviews or high-powered trials.

Sexual & reproductive · decreases · well replicated

Soy took off less than one hot flush a day

Across 62 randomised trials in 6,653 women, plant oestrogens as a group came to 1.31 fewer hot flushes a day, and soy on its own less than that. Night sweats did not improve.

What the study found

Soy's own effect was 0.79 fewer hot flushes a day

Across 62 randomised trials in 6,653 women, plant oestrogens as a group came to 1.31 fewer hot flushes a day, and soy on its own accounted for less than that. Night sweats did not improve at all, and vaginal dryness improved slightly.

The caveat · 46 of 62 trials at high risk of bias

Forty-six of the 62 trials, three-quarters of them, carried a high risk of bias in three or more quality domains. Against a typical starting point of several flushes a day, four-fifths of one is a real change and a small one. The night-sweats interval is wide enough to rule out almost nothing.