SubEx
Soy Isoflavones·Balance hormones·finding 16 of 26
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★★☆Single study — solid evidence, such as one good trial or a large observational dataset, but not replicated at the top tier.

Sexual & reproductive · no significant effect · single study

Soy did nothing for hot flushes after breast cancer

Five randomised trials in women who had had breast cancer compared soy against placebo and found no significant reduction in hot flushes.

What the study found

Soy did nothing for hot flushes in women who had had breast cancer

Five randomised trials in that population compared soy against placebo and found no significant reduction. It is the group with the strongest reason to want a non-hormonal option, and the group most often told to avoid oestrogen-like compounds altogether.

The caveat · The null's size was never reported

No pooled effect size was reported for these five trials, so the size of the null cannot be stated. The wider review they sit inside is a narrative synthesis rather than a meta-analysis for most of its outcomes. It was conducted at a naturopathic college, which has an interest in the answer.