Depression and anxiety scores did not move against placebo
Eleven trials and 312 people: depressive, anxiety and obsessive-compulsive symptoms all came out non-significant. The anxiety side rests on 70 people across four trials.
What the study found
Across eleven trials, inositol moved no mood or anxiety measure
Depressive, anxiety and obsessive-compulsive symptoms all came out non-significant against placebo. The anxiety side of that rests on 70 people across four trials, so this is a null from a very small base rather than a settled answer.
The caveat · No comparable review since 2013
Eleven trials and 312 people in total, and the authors name the small number of studies as their main limitation. The search closed in August 2013 and nothing comparable has replaced it. No pooled dose is reported, so these results should not be read across to the intakes used in polycystic ovary syndrome supplements.